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USC-OGP 2-DE database

Two-dimensional polyacrylamide gel electrophoresis database


USC-OGP 2-DE database 
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Searching in 'USC-OGP 2-DE database' for entry matching: P51966




USC-OGP 2-DE database:  P51966


P51966


General information about the entry
View entry in simple text format
Entry nameUB2L3_HUMAN
Primary accession numberP68036
Secondary accession number(s) P51966
integrated into USC-OGP 2-DE database on January 17, 2017 (release 1)
2D Annotations were last modified onJanuary 17, 2017 (version 1)
General Annotations were last modified on April 5, 2017 (version 2)
Name and origin of the protein
DescriptionRecName: Full=Ubiquitin-conjugating enzyme E2 L3; EC=2.3.2.23 {ECO:0000269|PubMed:20061386}; AltName: Full=E2 ubiquitin-conjugating enzyme L3; AltName: Full=L-UBC; AltName: Full=UbcH7; AltName: Full=Ubiquitin carrier protein L3; AltName: Full=Ubiquitin-conjugating enzyme E2-F1; AltName: Full=Ubiquitin-protein ligase L3;.
Gene nameName=UBE2L3
Synonyms=UBCE7, UBCH7
Annotated speciesHomo sapiens (Human) [TaxID: 9606]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
References
[1]   2D GEL CHARACTERIZATION
Author 1., Author 2.
Submitted (Mar-2011) to Current
2D PAGE maps for identified proteins
How to interpret a protein

PLATELET_6-11 {PLATELET 6-11}
Homo sapiens (Human)
PLATELET_6-11
  map experimental info
 
PLATELET_6-11

MAP LOCATIONS:
pI=8.23; Mw=16543

Cross-references
UniProtKB/Swiss-ProtP68036; UB2L3_HUMAN.



2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 0.0
Entry nameUB2L3_HUMAN
Primary accession numberP68036
Secondary accession number(s) B2R4A7 B4DDG1 B4DSZ4 E7EWS7 P51966 P70653 Q9HAV1
Sequence was last modified on October 11, 2004 (version 1)
Annotations were last modified on March 15, 2017 (version 139)
Name and origin of the protein
DescriptionRecName: Full=Ubiquitin-conjugating enzyme E2 L3; EC=2.3.2.23 {ECO:0000269|PubMed:20061386}; AltName: Full=E2 ubiquitin-conjugating enzyme L3; AltName: Full=L-UBC; AltName: Full=UbcH7; AltName: Full=Ubiquitin carrier protein L3; AltName: Full=Ubiquitin-conjugating enzyme E2-F1; AltName: Full=Ubiquitin-protein ligase L3;
Gene nameName=UBE2L3
Synonyms=UBCE7, UBCH7
Encoded onName=UBE2L3; Synonyms=UBCE7, UBCH7
Keywords3D-structure; Acetylation; Alternative splicing; ATP-binding; Complete proteome; Cytoplasm; Direct protein sequencing; Nucleotide-binding; Nucleus; Reference proteome; Transcription; Transcription regulation; Transferase; Ubl conjugation; Ubl conjugation pathway.
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLS81003; AAB36017.1; -; mRNA
EMBLX92962; CAA63538.1; -; mRNA
EMBLAJ000519; CAA04156.1; -; mRNA
EMBLAF300336; AAG17922.1; -; Genomic_DNA
EMBLCR456606; CAG30492.1; -; mRNA
EMBLAK293179; BAG56722.1; -; mRNA
EMBLAK299985; BAG61806.1; -; mRNA
EMBLAK311761; BAG34704.1; -; mRNA
EMBLAP000553; -; NOT_ANNOTATED_CDS; Genomic_DNA
EMBLAP000557; -; NOT_ANNOTATED_CDS; Genomic_DNA
EMBLAP000558; -; NOT_ANNOTATED_CDS; Genomic_DNA
EMBLCH471095; EAW59459.1; -; Genomic_DNA
EMBLBC053368; AAH53368.1; -; mRNA
CCDSCCDS13790.1; -. [P68036-1]; .
CCDSCCDS58795.1; -. [P68036-3]; .
CCDSCCDS58796.1; -. [P68036-2]; .
RefSeqNP_001243284.1; NM_001256355.1. [P68036-3]; .
RefSeqNP_001243285.1; NM_001256356.1. [P68036-2]; .
RefSeqNP_003338.1; NM_003347.3. [P68036-1]; .
UniGeneHs.108104; -; .
PDB1C4Z; X-ray; 2.60 A; D=1-154
PDB1FBV; X-ray; 2.90 A; C=1-154
PDB3SQV; X-ray; 3.30 A; C/D=1-154
PDB3SY2; X-ray; 3.27 A; C/D=1-154
PDB4Q5E; X-ray; 1.87 A; C=1-154
PDB4Q5H; X-ray; 2.00 A; C=1-154
PDB5HPT; X-ray; 2.84 A; C/F=2-154
PDBsum1C4Z; -; .
PDBsum1FBV; -; .
PDBsum3SQV; -; .
PDBsum3SY2; -; .
PDBsum4Q5E; -; .
PDBsum4Q5H; -; .
PDBsum5HPT; -; .
ProteinModelPortalP68036; -; .
SMRP68036; -; .
BioGrid113180; 136; .
DIPDIP-6124N; -; .
IntActP68036; 29; .
MINTMINT-5002693; -; .
STRING9606.ENSP00000344259; -; .
iPTMnetP68036; -; .
PhosphoSitePlusP68036; -; .
SwissPalmP68036; -; .
BioMutaUBE2L3; -; .
DMDM54039805; -; .
OGPP51966; -; .
UCD-2DPAGEP68036; -; .
EPDP68036; -; .
MaxQBP68036; -; .
PaxDbP68036; -; .
PeptideAtlasP68036; -; .
PRIDEP68036; -; .
TopDownProteomicsP68036-1; -. [P68036-1]; .
TopDownProteomicsP68036-2; -. [P68036-2]; .
DNASU7332; -; .
EnsemblENST00000342192; ENSP00000344259; ENSG00000185651. [P68036-1]; .
EnsemblENST00000458578; ENSP00000400906; ENSG00000185651. [P68036-3]; .
EnsemblENST00000545681; ENSP00000445931; ENSG00000185651. [P68036-2]; .
GeneID7332; -; .
KEGGhsa:7332; -; .
UCSCuc002zva.2; human. [P68036-1]; .
CTD7332; -; .
DisGeNET7332; -; .
GeneCardsUBE2L3; -; .
HGNCHGNC:12488; UBE2L3; .
HPAHPA045609; -; .
HPAHPA062415; -; .
MIM603721; gene; .
neXtProtNX_P68036; -; .
OpenTargetsENSG00000185651; -; .
Orphanet536; Systemic lupus erythematosus; .
PharmGKBPA37137; -; .
eggNOGKOG0422; Eukaryota; .
eggNOGCOG5078; LUCA; .
GeneTreeENSGT00760000119012; -; .
HOGENOMHOG000233455; -; .
HOVERGENHBG063308; -; .
InParanoidP68036; -; .
KOK04552; -; .
OMAADGQIAC; -; .
OrthoDBEOG091G0QDO; -; .
PhylomeDBP68036; -; .
TreeFamTF313043; -; .
BRENDA2.3.2.B6; 2681; .
ReactomeR-HSA-8866652; Synthesis of active ubiquitin: roles of E1 and E2 enzymes; .
ReactomeR-HSA-8866654; E3 ubiquitin ligases ubiquitinate target proteins; .
ReactomeR-HSA-983168; Antigen processing: Ubiquitination & Proteasome degradation; .
SignaLinkP68036; -; .
UniPathwayUPA00143; -; .
ChiTaRSUBE2L3; human; .
EvolutionaryTraceP68036; -; .
GeneWikiUBE2L3; -; .
GenomeRNAi7332; -; .
PROPR:P68036; -; .
ProteomesUP000005640; Chromosome 22; .
BgeeENSG00000185651; -; .
CleanExHS_UBE2L3; -; .
ExpressionAtlasP68036; baseline and differential; .
GenevisibleP68036; HS; .
GOGO:0005737; C:cytoplasm; IDA:UniProtKB; .
GOGO:0005829; C:cytosol; IDA:HPA; .
GOGO:0070062; C:extracellular exosome; IDA:UniProtKB; .
GOGO:0005654; C:nucleoplasm; TAS:Reactome; .
GOGO:0005634; C:nucleus; IDA:UniProtKB; .
GOGO:0000151; C:ubiquitin ligase complex; TAS:UniProtKB; .
GOGO:0005524; F:ATP binding; IEA:UniProtKB-KW; .
GOGO:0019899; F:enzyme binding; TAS:UniProtKB; .
GOGO:0003723; F:RNA binding; IDA:UniProtKB; .
GOGO:0003713; F:transcription coactivator activity; IDA:UniProtKB; .
GOGO:0061631; F:ubiquitin conjugating enzyme activity; IDA:MGI; .
GOGO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB; .
GOGO:0097027; F:ubiquitin-protein transferase activator activity; IGI:ParkinsonsUK-UCL; .
GOGO:0004842; F:ubiquitin-protein transferase activity; IDA:UniProtKB; .
GOGO:0044770; P:cell cycle phase transition; IMP:UniProtKB; .
GOGO:0008283; P:cell proliferation; IMP:UniProtKB; .
GOGO:0006464; P:cellular protein modification process; TAS:UniProtKB; .
GOGO:0071385; P:cellular response to glucocorticoid stimulus; IDA:UniProtKB; .
GOGO:0071383; P:cellular response to steroid hormone stimulus; IMP:UniProtKB; .
GOGO:1903955; P:positive regulation of protein targeting to mitochondrion; IMP:ParkinsonsUK-UCL; .
GOGO:0031398; P:positive regulation of protein ubiquitination; IGI:ParkinsonsUK-UCL; .
GOGO:0051443; P:positive regulation of ubiquitin-protein transferase activity; IGI:ParkinsonsUK-UCL; .
GOGO:0070979; P:protein K11-linked ubiquitination; IDA:UniProtKB; .
GOGO:0000209; P:protein polyubiquitination; IDA:UniProtKB; .
GOGO:0016567; P:protein ubiquitination; IDA:UniProtKB; .
GOGO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IEA:Ensembl; .
GOGO:0006355; P:regulation of transcription; DNA-templated; IDA:UniProtKB
GOGO:0006351; P:transcription; DNA-templated; IEA:UniProtKB-KW
GOGO:0006511; P:ubiquitin-dependent protein catabolic process; TAS:UniProtKB; .
Gene3D3.10.110.10; -; 1; .
InterProIPR000608; UBQ-conjugat_E2; .
InterProIPR023313; UBQ-conjugating_AS; .
InterProIPR016135; UBQ-conjugating_enzyme/RWD; .
PfamPF00179; UQ_con; 1; .
SUPFAMSSF54495; SSF54495; 1; .
PROSITEPS00183; UBIQUITIN_CONJUGAT_1; 1; .
PROSITEPS50127; UBIQUITIN_CONJUGAT_2; 1; .



USC-OGP 2-DE database image


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Database constructed and maintained by Angel Garcia, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the ExPASy web server

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